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    Tributyl-O-acetylcitrat Produkt Beschreibung

    Acetyl tributyl citrate Struktur
    77-90-7
    CAS-Nr.
    77-90-7
    Bezeichnung:
    Tributyl-O-acetylcitrat
    Englisch Name:
    Acetyl tributyl citrate
    Synonyma:
    ATBC;Blo-trol;Estaflex;FEMA 3080;Uniplex 84;citroflexa;Citroflex A;citroflexa4;Citroflex A 4;acetylbutylcitrate
    CBNumber:
    CB0408022
    Summenformel:
    C20H34O8
    Molgewicht:
    402.48
    MOL-Datei:
    77-90-7.mol

    Tributyl-O-acetylcitrat Eigenschaften

    Schmelzpunkt:
    -59 °C
    Siedepunkt:
    327 °C
    Dichte
    1.05 g/mL at 25 °C (lit.)
    Dampfdruck
    0.26 psi ( 20 °C)
    Brechungsindex
    n20/D 1.443(lit.)
    FEMA 
    3080 | TRIBUTYL ACETYLCITRATE
    Flammpunkt:
    >230 °F
    storage temp. 
    Store below +30°C.
    L?slichkeit
    Not miscible with water, miscible with ethanol (96 per cent) and with methylene chloride.
    Aggregatzustand
    neat
    Wasserl?slichkeit
    <0.1 g/100 mL
    FreezingPoint 
    -80℃
    JECFA Number
    630
    BRN 
    2303316
    InChIKey
    QZCLKYGREBVARF-UHFFFAOYSA-N
    CAS Datenbank
    77-90-7(CAS DataBase Reference)
    NIST chemische Informationen
    1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester(77-90-7)
    EPA chemische Informationen
    Acetyl tributyl citrate (77-90-7)

    Sicherheit

    S-S?tze: 24/25
    WGK Germany  3
    RTECS-Nr. TZ8330000
    HS Code  29181500
    Giftige Stoffe Daten 77-90-7(Hazardous Substances Data)

    Tributyl-O-acetylcitrat Chemische Eigenschaften,Einsatz,Produktion Methoden

    S-S?tze Betriebsanweisung:

    S24/25:Berührung mit den Augen und der Haut vermeiden.

    Chemische Eigenschaften

    clear colorless liquid

    Chemische Eigenschaften

    Acetyltributyl citrate is a clear, odorless, practically colorless, oily liquid.

    Chemische Eigenschaften

    Tributyl acetylcitrate has a very faint, sweet, herbaceous odor. At high levels (e.g., 1000 ppm emulsion in water), it has a mild, fruity, nondescript flavor.

    Chemische Eigenschaften

    Acetyl tributyl citrate (ATBC) is a colorless, odorless liquid. Its water solubility is less than 0.002 g/100 mL, but it is soluble in organic solvents.

    Verwenden

    These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

    Verwenden

    Labelled Tributyl O-Acetylcitrate (T772950). Topical pharmaceutical formulation anesthetic surfactant ester.

    Verwenden

    plasticizer flavoring agent

    Definition

    Aqueous-based pharmaceutical coat- ings.

    synthetische

    From citric acid via the tributyl ester followed by acetylation.

    Vorbereitung Methode

    Acetyltributyl citrate is prepared by the esterification of citric acid with butanol followed by acylation with acetic anhydride.

    Allgemeine Beschreibung

    Tributyl 2-acetylcitrate is a hydrophobic biodegradable plasticizer, that is usually synthesized by esterification of citric acid. Pharmaceutically, it is used as an excipient, which is generally applied as a thin film over the tablets or capsules.
    Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

    Pharmazeutische Anwendungen

    Acetyltributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations.

    Sicherheitsprofil

    When heated to decomposition it emits acrid smoke and irritating fumes. ADD750

    Sicherheit(Safety)

    and films intended for direct food contact. It is also used in selfadhesive thin films used for topical delivery systems. It is generally regarded as a relatively nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.
    LD50 (cat, oral): >50 mL/kg
    LD50 (mouse, IP): >4 g/kg
    LD50 (rat, oral): >31.5 g/kg

    Carcinogenicity

    The chronic toxicity of ATBC was evaluated in rats fed diets containing 200, 2000, or 20,000 ppm of ATBC for 2 years. There were no treatment- related lesions in any organs examined.

    Lager

    Acetyltributyl citrate should be stored in a well-closed container in a cool, dry location at temperatures not exceeding 38℃. When stored in accordance with these conditions, acetyltributyl citrate is a stable product.

    Inkompatibilit?ten

    Acetyltributyl citrate is incompatible with strong alkalis and oxidizing materials.

    Regulatory Status

    Included in FDA Inactive Ingredients Database (oral capsules and tablets). Included in nonparenteral medicines licensed in the UK. Approved in the USA for direct food contact in food films.

    Tributyl-O-acetylcitrat Upstream-Materialien And Downstream Produkte

    Upstream-Materialien

    Downstream Produkte


    Tributyl-O-acetylcitrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

    Global( 289)Lieferanten
    Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
    Hefei TNJ Chemical Industry Co.,Ltd.
    +86-0551-65418679
    86-0551-65418697 info@tnjchem.com China 3000 55
    Henan Tianfu Chemical Co.,Ltd.
    0371-55170693
    0371-55170693 info@tianfuchem.com China 22607 55
    Hangzhou FandaChem Co.,Ltd.
    008615858145714
    +86-571-56059825 fandachem@gmail.com CHINA 9143 55
    career henan chemical co
    +86-0371-55982848
    sales@coreychem.com China 29953 58
    SHANDONG ZHI SHANG CHEMICAL CO.LTD
    +86 18953170293
    +86 0531-67809011 sales@sdzschem.com CHINA 2940 58
    Hubei Jusheng Technology Co.,Ltd.
    86-18871470254
    027-59599243 linda@hubeijusheng.com CHINA 28229 58
    Hebei Guanlang Biotechnology Co., Ltd.
    +8619930503282
    alice@crovellbio.com China 5943 58
    Xiamen AmoyChem Co., Ltd
    +86 592-605 1114
    sales@amoychem.com CHINA 6369 58
    Hubei xin bonus chemical co. LTD
    86-13657291602
    027-59338440 linda@hubeijusheng.com CHINA 23035 58
    Shandong chuangyingchemical Co., Ltd.
    18853181302
    sale@chuangyingchem.com CHINA 5917 58

    77-90-7(Tributyl-O-acetylcitrat)Verwandte Suche:


    • tributyl2-(acetyloxy)-1,2,3-propanetricarboxylicacid
    • tributylcitrateacetate
    • Uniplex 84
    • butyl acetylcitrate
    • TRIBUTYL ACETYLCITRATE 98+%
    • CITROFLEX A4 FOR GAS CHROMATOGRAPHY &
    • FEMA 3080
    • ATBC
    • Tributyl O-acetylcitrate,Acetyl tributyl citrate, Tributyl 2-acetylcitrate
    • Tributyl 2-acetylcitrate,Acetyl tributyl citrate
    • Acetyltributyl Citrate (500 mg)
    • O-ACETYLTRIBUTYLCITRATE
    • TRI-N-BUTYLACETYLCITRATE
    • Acetyl tributyl citrate, Tributyl 2-acetylcitrate
    • O-ACETYLCITRIC ACID TRIBUTYL ESTER
    • TRIBUTYL ACETYLCITRATE
    • TRIBUTYL 2-ACETOXY-1,2,3-PROPANETRICARBOXYLATE
    • TRIBUTYL 2-ACETYLCITRATE
    • TRIBUTYL O-ACETYLCITRATE
    • Acetyltributylcitrat
    • tributyl 2-acetyloxypropane-1,2,3-tricarboxylate
    • Tributyl O-acetylcitrate, 98.5%
    • tributyl 2-acetoxypropane-1,2,3-tricarboxylate
    • TRIBUTYLACETYL CITRATE FOR SYNTHESIS
    • Tributyl O-acetylcitrate 98%
    • Acetyl tributyl citrate Tributyl O-Acetylcitrate O-Acetylcitric Acid Tributyl Ester ATBC
    • 2-acetyltributylcitrate
    • Acetyl butyl citrate
    • Acetyl tributyl citrate1,2,3-propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester
    • acetylbutylcitrate
    • Acetylcitric acid, tributyl ester
    • acetylcitricacid,tributylester
    • Acetyl Tributyl Citrate(Reach)
    • acetylcitricacidtributylester
    • Blo-trol
    • Citric acid, tributyl ester, acetate
    • citricacid,tributylester,acetate
    • Citroflex A
    • Citroflex A 4
    • citroflexa
    • citroflexa4
    • Estaflex
    • Pfizer citroflex A-4
    • Tributyl 2-(acetyloxy)-1,2,3-propanetricarboxylate
    • Tributyl 2-(acetyloxy)-1,2,3-propanetricarboxylic acid
    • Tributyl acetylicitrate
    • Tributyl citrate acetate
    • tributyl2-(acetyloxy)-1,2,3-propanetricarboxylate
    • ACETYL TRIBUTYL CITRATE
    • ACETYL TRI-N-BUTYL CITRATE
    • Tributyl-Acethylcitrate
    • Acetyl tributyl citrate 10g [77-90-7]
    • 1,2,3-Propanetricarboxylic acid, 2-acetoxy-, tributyl ester
    • 1,2,3-Propanetricarboxylicacid,2-(acetyloxy)-,tributylester
    • 2-(Acetyloxy)-1,2,3-propane tricarboxylic acid, tributyl ester
    • 2,3-propanetricarboxylicacid,2-(acetyloxy)-tributylester
    • 2-Acetoxy-1,2,3-propanetricarboxylic acid tributyl ester
    • 2-acetoxy-1,2,3-propanetricarboxylicacidtributylester
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