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    Piperin Produkt Beschreibung

    Piperine Struktur
    94-62-2
    CAS-Nr.
    94-62-2
    Bezeichnung:
    Piperin
    Englisch Name:
    Piperine
    Synonyma:
    Piperin;PIPERINE;FEMA 2909;Bioperine;NSC 21727;PIPERLINE;PIPERINE(P);Piperine>Piperine,99%;Piperine,98%
    CBNumber:
    CB1249813
    Summenformel:
    C17H19NO3
    Molgewicht:
    285.34
    MOL-Datei:
    94-62-2.mol

    Piperin Eigenschaften

    Schmelzpunkt:
    131-135 °C(lit.)
    Siedepunkt:
    427.77°C (rough estimate)
    Dichte
    1.0864 (rough estimate)
    FEMA 
    2909 | PIPERINE
    Brechungsindex
    1.5400 (estimate)
    storage temp. 
    Sealed in dry,Room Temperature
    L?slichkeit
    0.04g/l
    pka
    12.22(at 18℃)
    Aggregatzustand
    Crystalline Powder
    Farbe
    Off-white to tan or yellow-tan
    Wasserl?slichkeit
    40 mg/L (18 ºC)
    Merck 
    14,7472
    JECFA Number
    1600
    BRN 
    90741
    Stabilit?t:
    Stable. Incompatible with strong oxidizing agents.
    InChIKey
    MXXWOMGUGJBKIW-YPCIICBESA-N
    CAS Datenbank
    94-62-2(CAS DataBase Reference)
    NIST chemische Informationen
    Piperine(94-62-2)
    EPA chemische Informationen
    2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)- (94-62-2)
    Sicherheit
    • Risiko- und Sicherheitserkl?rung
    • Gefahreninformationscode (GHS)
    Kennzeichnung gef?hrlicher Xn,Xi,N
    R-S?tze: 22-21/22-20/21/22-51/53
    S-S?tze: 22-24/25-36/37-36-61
    RIDADR  UN 3077 9 / PGIII
    WGK Germany  3
    RTECS-Nr. TN2321500
    Hazard Note  Irritant
    TSCA  Yes
    HS Code  29399990
    Toxizit?t LD50 orally in Rabbit: 514 mg/kg
    Bildanzeige (GHS)
    Alarmwort Warnung
    Gefahrenhinweise
    Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
    H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
    H361 Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Reproduktionstoxizit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
    H411 Giftig für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 2
    Sicherheit
    P201 Vor Gebrauch besondere Anweisungen einholen.
    P264 Nach Gebrauch gründlich waschen.
    P264 Nach Gebrauch gründlich waschen.
    P270 Bei Gebrauch nicht essen, trinken oder rauchen.
    P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
    P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
    P405 Unter Verschluss aufbewahren.
    P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

    Piperin Chemische Eigenschaften,Einsatz,Produktion Methoden

    R-S?tze Betriebsanweisung:

    R22:Gesundheitssch?dlich beim Verschlucken.
    R21/22:Gesundheitssch?dlich bei Berührung mit der Haut und beim Verschlucken.
    R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

    S-S?tze Betriebsanweisung:

    S22:Staub nicht einatmen.
    S24/25:Berührung mit den Augen und der Haut vermeiden.
    S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

    Beschreibung

    Piperine is an alkaloid responsible for the taste and fl avor of pepper. In pure form it exists as a yellow to pale-yellow crystal, with a burning taste and pungent order. It is found naturally in plants in the Piperaceae family, particularly Piper nigrum (black pepper) and Piper longum (Indian long pepper). Piper nigrum is a perennial woody vine that grows to approximately 30 feet. It produces spikelike flowers that hold berries called peppercorns.

    Chemische Eigenschaften

    light yellow powder

    Chemische Eigenschaften

    Piperine is odorless. It is tasteless at first, but develops a burning aftertaste of pepper.

    Occurrence

    Reported found in black pepper; also in Piper longum, Piper officinarum, Piper lowong BI., Piper famechoni, Piper chaba and the leaves of Rhododendron fauriae var. rupescens.

    History

    Hans Christian Oersted (1777 1851) isolated piperine from black pepper in 1819 and published his findings in 1820. Oersted extracted a resin from pepper plants with alcohol, formed a soluble saltby adding hydrochloric acid with alcohol, and then separated piperine from solution by precipitation and distillation. In 1882, Leopold Rügheimer (1850 1917) synthesized piperine from piperinic acid chloride and piperidine. The complete synthesis of piperine was reported in 1894 by Albert Ladenburg (1842 1911) and M. Scholtz. Ladenburg and Scholtz used piperonal (C8H6O3) and acetaldehyde (CH3CHO) to produce piperinic acid (C12H10O4), which was then reacted with thionyl chloride (COCl2) and piperidine (C5H11N) to produce piperine.

    Verwenden

    Piperine is used in granular formulations as a pesticide against small animals such as dogs, cats, skunks, raccoons, and squirrels. Piperine pesticides are nontoxic and operate as a repellant when animals smell or test them. Piperine is also incorporated with other compounds to make insecticides; it is effective against houseflies, lice, and various other pests.
    Piperine has been used medicinally for thousands of years and this continues today. It is used to treat asthma and chronic bronchitis. It also has putative analgesic and antiinfl ammatory properties that stem from its antioxidant properties. Research is examining the use of piperine in treating malaria. Antiepilepsirine is a derivative of piperine that is used to treat different types of epilepsy, especially in China. A current area of interest is the efficacy of piperine in increasing the bioavailability of certain nutrients and drugs. It is thought to possibly aid digestion and increase the absorption in the digestive tract of numerous drugs used as cancer treatments, antihistamines, steroidal inflammation reducers, and antibiotics.

    Verwenden

    The alkaloid which gives pepper its spiciness, and has been used as an organic insecticide.

    Verwenden

    analeptic, antibacterial

    Verwenden

    antipsychotic

    Verwenden

    A black pepper extract TRPV1 activator

    synthetische

    From piperoyl chloride and piperidine.

    Sicherheitsprofil

    Poison by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

    l?uterung methode

    Piperine crystallises as light yellow crystals from EtOH or EtOAc (m 132o), aqueous EtOH (m 128-129o), Et2O (m129o), or*benzene/ligroin. [Beilstein 20 H 79, 20 I 23, 20 II 53, 20 III/IV 1341, 20/3 V 469.]

    Einzelnachweise

    Oersred., Schweigger's Journal, 29, 80 (1819)
    Fliickiger, Hanbury., Pharmacographica, 584 London (1879)
    Stenhouse., Pharm. J., 14,363 (1855)
    Cazeneuve, Caillot., Bull. Soc. Chim. Fr., 27,291 (1877)
    Riigheimer., Ber., 15, 1391 (1882)
    Peinemann., Arch. Pharm., 234, 245 (1896)
    Newman., Chem. Products, 16,379 (1953)

    Piperin Upstream-Materialien And Downstream Produkte

    Upstream-Materialien

    Downstream Produkte


    Piperin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

    Global( 341)Lieferanten
    Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
    Capot Chemical Co.,Ltd.
    +86(0)13336195806 +86-571-85586718
    +86-571-85864795 sales@capotchem.com China 20012 60
    Henan Tianfu Chemical Co.,Ltd.
    0371-55170693
    0371-55170693 info@tianfuchem.com China 22607 55
    Shanghai Zheyan Biotech Co., Ltd.
    18017610038
    zheyansh@163.com CHINA 3623 58
    career henan chemical co
    +86-0371-55982848
    sales@coreychem.com China 29953 58
    Wuhan Boyuan Import & Export Co., LTD
    +8618033787409
    0311-89850048 Mike@whby-chem.com China 298 58
    SHANDONG ZHI SHANG CHEMICAL CO.LTD
    +86 18953170293
    +86 0531-67809011 sales@sdzschem.com CHINA 2940 58
    Chengdu Biopurify Phytochemicals Ltd.
    18482058008 18080483897
    maggie@biopurify.com China 2712 58
    Nanjing Dolon Biotechnology Co.,Ltd.
    18905173768
    sales@dolonchem.com CHINA 2972 58
    Hubei Jusheng Technology Co.,Ltd.
    86-18871470254
    027-59599243 linda@hubeijusheng.com CHINA 28229 58
    Chongqing Chemdad Co.,Ltd
    +86-19923101450
    sales@chemdad.com CHINA 4000 58

    94-62-2(Piperin)Verwandte Suche:


    • (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
    • FEMA 2909
    • 5-BENZO[1,3]DIOXOL-5-YL-1-PIPERIDIN-1-YL-PENTA-2,4-DIEN-1-ONE
    • PIPERINE
    • N-PIPEROYLPIPERIDIN
    • 1-PIPERONYLPIPERIDINE
    • 1-PIPEROYLPIPERIDINE
    • 1-PIPERYLPIPERIDINE
    • 1-[5-(1,3-BENZODIOXOL-5-YL)-2,4-PENTADIENOYL]PIPERIDINE
    • 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-,(e,e)-piperidin
    • 1,3-Benzodioxol-5-yl-1-oxo-2,4-pentadienyl-piperidine
    • 5-(1,3-BENZODIOXOL-5-YL)-1-OXO-2E,4E-PENTADIENYL-PIPERD.
    • PIPERIDINE,1-PIPERONYL-
    • Natural piperine
    • (1-piperidinyl)-,(2E, 4E)-
    • 2,4-Pentadien-1-one,5-(1,3-benzodioxol-5-yl)-1-
    • Bioperine
    • (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine
    • (E,E)-5-(3,4-Methylenedioxyphenyl)-2,4-pentadienoylpiperidide
    • 2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)-
    • (2E,4E)-1-(1-Piperidinyl)-5-(1,3-benzodioxole-5-yl)-2,4-pentadiene-1-one
    • 1-[(2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine
    • Piperine,99%
    • (E,E)-1-Piperoylpiperidine
    • Piperylpiperidine
    • Piperine(1-Piperoylpiperidine)
    • (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one
    • NSC 21727
    • 1-[5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine 1-Piperoylpiperidine 1-Piperylpiperidine
    • (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one
    • 1,3-benzodioxol-5-yl-1-oxo-2,4-pentadienyl-piperine
    • 1-[(2E,4E)-5-(1,3-Benzodioxol-5-yl)-2,4-pentadienoyl]piperidine
    • 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-,(e,e)-piperidin
    • 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-,(E,E)-Piperidine
    • 1-piperoyl-,(e,e)-piperidin
    • 1-trans,trans-piperinoyl-piperidine
    • Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-
    • Piperidine, 1-piperoyl-, (E,E)-
    • Piperin
    • PIPERINE 97+%
    • Piperine,98%
    • Piperidine, 1-(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl-
    • 1-piperinoylpiperidine
    • PIPERINE(P)
    • PIPERINE(RG)
    • PIPERLINE
    • Piperine SynonyMs (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
    • Piperine (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
    • Hot sale Piperine 90%min CAS NO.94-62-2
    • Piperine 94-62-2
    • Piperine>
    • Piperine CRS
    • Piperine USP/EP/BP
    • Black Pepper Extract 95% Piperine
    • (E,E)-piperine
    • 94-62-2
    • 84-62-2
    • Piperidines
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