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    Bilobalide Produkt Beschreibung

    Bilobalide Struktur
    33570-04-6
    CAS-Nr.
    33570-04-6
    Englisch Name:
    Bilobalide
    Synonyma:
    BILOBALID;BILOBALIDE;VITEXICARPIM;Bilobalide A;(-)-BILOBALIDE;BILOBALIDE(SH);Bilobalide >BILOBALIDE(AHP);Bilobalide USP/EP/BP;Bilobalide 33570-04-6
    CBNumber:
    CB1688713
    Summenformel:
    C15H18O8
    Molgewicht:
    326.3
    MOL-Datei:
    33570-04-6.mol

    Bilobalide Eigenschaften

    Schmelzpunkt:
    >300°
    alpha 
    57820 -64.3° (c = 2 in acetone)
    Siedepunkt:
    651.7±55.0 °C(Predicted)
    Dichte
    1.56±0.1 g/cm3(Predicted)
    storage temp. 
    −20°C
    pka
    11.74±0.40(Predicted)
    Aggregatzustand
    neat
    Merck 
    14,1220
    CAS Datenbank
    33570-04-6(CAS DataBase Reference)

    Sicherheit

    S-S?tze: 24/25
    WGK Germany  3
    RTECS-Nr. LV1665000
    10
    HS Code  29322090

    Bilobalide Chemische Eigenschaften,Einsatz,Produktion Methoden

    Beschreibung

    Bilobalide is a sesquiterpene lactone which is found in extracts of G. biloba. It has been shown to protect against cerebral edema, decrease cortical infarct volume, and reduce cerebral ischemic damage. Bilobalide, at 10 μM, reduces the release of glycine and glutamate from hippocampal slices under ischemic conditions. It also activates the rat constitutive androstane receptor at 100 μM and increases the levels and activities of several cytochrome P450 isoforms in rat liver microsomes.

    Definition

    ChEBI: A terpenoid trilactone found in extracts of Ginkgo biloba.

    Enzyminhibitor

    This plant natural product (FW = 326.30 g/mol; CAS 33570-04-6) from the gingko tree (Ginkgo biloba) is a terpene trilactone that exhibits anticonvulsant properties. Bilobalide has multiple mechanisms of action (e.g., acting as a GABAA receptor antagonist (/1), preserving mitochondrial ATP synthesis, inhibiting staurosporine-induced apoptotic damage, suppressing hypoxia-induced membrane deterioration in the brain, and increasing the expression the mitochondrial DNA-encoded COX III subunit of cytochrome c oxidase and the ND1 subunit of NADH dehydrogenase). Bilobalide was later synthesized in E. J. Corey’s laboratory in the late 1980s.

    Bilobalide Upstream-Materialien And Downstream Produkte

    Upstream-Materialien

    Downstream Produkte


    Bilobalide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

    Global( 253)Lieferanten
    Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
    Shanghai Zheyan Biotech Co., Ltd.
    18017610038
    zheyansh@163.com CHINA 3623 58
    career henan chemical co
    +86-0371-55982848
    sales@coreychem.com China 29953 58
    Chengdu Biopurify Phytochemicals Ltd.
    18482058008 18080483897
    maggie@biopurify.com China 2712 58
    Hubei Jusheng Technology Co.,Ltd.
    86-18871470254
    027-59599243 linda@hubeijusheng.com CHINA 28229 58
    Chongqing Chemdad Co.,Ltd
    +86-19923101450
    sales@chemdad.com CHINA 4000 58
    Shaanxi Pioneer Biotech Co., Ltd .
    86-13259417953(Whatsapp/Wechat) 86-13259417953(Whatsapp)
    029-84385017 sales@pioneerbiotech.com CHINA 3001 58
    NanJing Spring & Autumn Biological Engineering CO., LTD.
    0086 13815430202 0086 13815430202
    sale02@cqherb.com CHINA 376 58
    BOC Sciences
    1-631-485-4226
    1-631-614-7828 inquiry@bocsci.com United States 19752 58
    Chongqing Chemdad Co., Ltd
    +86-13650506873
    sales@chemdad.com CHINA 37282 58
    Shanghai Standard Technology Co., Ltd.
    18502101150
    +86-21-57127007-6606 ft-sales@nature-standard.com CHINA 1923 58

    33570-04-6()Verwandte Suche:


    • BILOBALID
    • 4H,5aH,9H-Furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (3aS,5aR,8R,8aS,9R,10aS)-
    • (5AR- (3AS*,5AΑ,8B,8AS*,9A,10AΑ))- 9-(1,1-DIMETHYLETHYL)- 10,10A-DIHYDRO- 8,9-DIHYDROXY- 4H,5AH,9H-FURO[2,3-B]FURO[3',2':2,3]CYCLOPENTA[1,2-C]FURAN- 2,4,7(3H,8H)-TRIONE
    • (-)-Bilobalide, 98%, from Ginkgo biloba L.
    • Bilobalide 33570-04-6
    • (-)-BILOBALIDE
    • BILOBALIDE
    • 5,3'-DIHYDROXY-3,6,7,4'-TETRAMETHOXYFLAVONE
    • 4H,5AH,9H-FURO[2,3-B]FURO[3',2':2,3]CYCLOPENTA[1,2-C]FURAN-2,4,7(3H,8H)-TRIONE,9-(1,1-DIMETHYLETHYL)-10,10A-DIHYDRO-8,9-DIHYDROXY-, [5AR-(3AS*,5A,8,8AS*,9,10A)]-
    • 3',5-DIHYDROXY-3,4',6,7-TETRAMETHOXY FLAVONE
    • VITEXICARPIM
    • BILOBALIDE(SH)
    • 4H,5aH,9H-Furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione,9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-,[5aR-(3aS*,5aα,8β,8aS*,9α,10aα)]-
    • (-)-bilobalidefromginkgoleaves
    • BILOBALIDE: 4H,5AH,9H-FURO[2,3-B]FURO[3',2':2,3]CYCLOPENTA[1,2-C]FURAN-2,4,7(3H,8H)-TRIONE,9-(1,1-DIMETHYLETHYL)-10,10A-DIHYDRO-8,9-DIHYDROXY-, [5AR-(3AS*,5A,8,8AS*,9,10A)]-,
    • (-)-bilobalide from ginkgo biloba leaves
    • BILOBALIDE(AHP)
    • Bilobalide A
    • (-)-Bilobalide, froM Ginkgo biloba
    • Bilobalide >
    • Bilobalide USP/EP/BP
    • (-)-Bilobalide from Ginkgo biloba leaves
    • 33570-04-6
    • C15H18O9
    • C15H18O8
    • Inhibitors
    • chemical reagent
    • pharmaceutical intermediate
    • phytochemical
    • reference standards from Chinese medicinal herbs (TCM).
    • standardized herbal extract
    • Heterocycles
    • Biochemicals Found in Plants
    • Isoprenoid/terpenoid
    • Nutrition Research
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