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    Cilnidipine Produkt Beschreibung

    Cilnidipine Struktur
    132203-70-4
    CAS-Nr.
    132203-70-4
    Englisch Name:
    Cilnidipine
    Synonyma:
    CiL;ATELEC;SISCARD;CINALONG;FRC-8653;Sidipine;FRG 8653;nidipine;ilnidipine;CILNDIPINE
    CBNumber:
    CB2193117
    Summenformel:
    C27H28N2O7
    Molgewicht:
    492.52
    MOL-Datei:
    132203-70-4.mol

    Cilnidipine Eigenschaften

    Schmelzpunkt:
    97-99°C
    Siedepunkt:
    652.6±55.0 °C(Predicted)
    Dichte
    1.240±0.06 g/cm3(Predicted)
    storage temp. 
    Keep in dark place,Sealed in dry,Room Temperature
    L?slichkeit
    H2O: ≤2mg/mL
    Aggregatzustand
    powder
    pka
    2.61±0.70(Predicted)
    Farbe
    light yellow
    Merck 
    14,2275
    InChIKey
    KJEBULYHNRNJTE-DHZHZOJOSA-N
    CAS Datenbank
    132203-70-4(CAS DataBase Reference)
    Sicherheit
    • Risiko- und Sicherheitserkl?rung
    • Gefahreninformationscode (GHS)
    Kennzeichnung gef?hrlicher Xi
    R-S?tze: 41
    S-S?tze: 26-39
    WGK Germany  3
    RTECS-Nr. US7975550
    HS Code  29333990
    Toxizit?t LD50 in male, female mice, rats (mg/kg): 5000, 5000, 5000, 4412 orally; 5000 all species s.c.; 1845, 2353, 441, 426 i.p. (Wada)
    Bildanzeige (GHS)
    Alarmwort Achtung
    Gefahrenhinweise
    Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
    H318 Verursacht schwere Augensch?den. Schwere Augensch?digung Kategorie 1 Achtung P280, P305+P351+P338, P310
    Sicherheit
    P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
    P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

    Cilnidipine Chemische Eigenschaften,Einsatz,Produktion Methoden

    Beschreibung

    Cilnidipine is a dihydropyridine calcium antagonist introduced for the treatment of essential and severe hypertension and hypertension associated with renopathy. Cilnidipine has been demonstrated to exert a potent vasodilating effect by blocking calcium influx via dihydropyridine-sensitive, voltage-dependent calcium channels. Compared to nifedipine and nicardipine, cilnidipine is superior, especially for long-term treatment, due to its characteristics of slow onset and long duration with less cardiodepressant activity. Cilnidipine is reportedly well tolerated with low toxicity. It may also be useful in ischemic heart disease.

    Chemische Eigenschaften

    Yellow Crystalline Solid

    Originator

    Fujirebio (Japan)

    Verwenden

    A dihydropyridine calcium channel blocker

    Verwenden

    antihypertensive;dihydropyridine calcium channel blocker

    Definition

    ChEBI: A diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive.

    Trademarks

    Cinalong;Siscard;Atelec

    Biologische Aktivit?t

    Dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. Lowers mean blood pressure and reduces the size of cerebral infarction in the rat model of focal brain ischemia.

    Cilnidipine Upstream-Materialien And Downstream Produkte

    Upstream-Materialien

    Downstream Produkte


    Cilnidipine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

    Global( 295)Lieferanten
    Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
    Henan Tianfu Chemical Co.,Ltd.
    0371-55170693
    0371-55170693 info@tianfuchem.com CHINA 22607 55
    Hangzhou FandaChem Co.,Ltd.
    008615858145714
    +86-571-56059825 fandachem@gmail.com CHINA 8882 55
    Shanxi Naipu Import and Export Co.,Ltd
    +8613734021967
    kaia@neputrading.com CHINA 1011 58
    career henan chemical co
    +86-371-86658258
    sales@coreychem.com CHINA 29961 58
    HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
    +86 19930599843
    cindy@hbyingong.com CHINA 408 58
    Hebei Jimi Trading Co., Ltd.
    +86 319 5273535
    bestoneforyou@sina.com CHINA 292 58
    Hebei Guanlang Biotechnology Co., Ltd.
    +8619930503282
    sales3@crovellbio.com China 5361 58
    Shandong chuangyingchemical Co., Ltd.
    18853181302
    sale@chuangyingchem.com CHINA 5917 58
    Chongqing Chemdad Co., Ltd
    +86-13650506873
    sales@chemdad.com CHINA 37282 58
    Alchem Pharmtech,Inc.
    8485655694
    sales@alchempharmtech.com United States 63726 58

    132203-70-4()Verwandte Suche:


    • ATELEC
    • (+/-)-(e)-cinnamyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
    • O3-(2-Methoxyethyl) O5-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-(2-methoxyethyl)5-[(E)-3-phenyl-2-propenyl] ester
    • 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-(2-methoxyethyl)5-[(E)-3-phenyl-2-propenyl] ester
    • Frc 8653,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (2E)-3-phenyl-2-propenyl ester
    • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl Ester 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
    • ilnidipine
    • 3-CinnaMyl 5-(2-Methoxyethyl) 2,6-diMethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    • 3-Cinnamyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylat
    • 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID 2-METHOXYETHYL (2E)-3-PHENYL-2-PROPENYL ESTER
    • SISCARD
    • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-methoxyethyl) 5-[(2E)-3-phenyl-2-propen-1-yl] ester
    • 3-Cinnamyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxy
    • CINALONG
    • CILNIDIPINE
    • FRC-8653
    • 2,6-dimethyl-4-(3-nitrophenyl)-5-(3-phenylprop-2-enoxymethyl)-1,4-dihydropyridine-3-carboxylic acid 2-methoxyethyl ester
    • Sidipine
    • Cilnidipine (FRC-8653)
    • Cilnidipine Whatsapp
    • CILNDIPINE
    • (e)-(+-)-ethoxyethyl3-phenyl-2-propenyleste
    • 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-m
    • Cinildipine
    • CINILDPINE
    • Cinidipine
    • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl Ester, FRC-8653, Atelec, Cinalong, Siscard,
    • CILNIDPINE
    • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl (2E)-3-phenyl-2-propenyl ester
    • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 3-phenyl-2-propenyl ester, (E)-
    • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 3-phenyl-2-propenyl ester, (E)-(+-)-
    • clinidipine
    • FRG 8653
    • Cilnidipine and intermediates
    • Cilnidipine >
    • Cilnidipine RS
    • CiL
    • nidipine
    • 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
    • Cilnidipine USP/EP/BP
    • 132203-70-4
    • Dihydropyridine Class Chemicals
    • Intermediates & Fine Chemicals
    • Pharmaceuticals
    • Calcium channel
    • API
    • FRC 8653
    • Dihydropyridine
    • APIs
    • Active Pharmaceutical Ingredients
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