• ChemicalBook
    Chinese Japanese Germany Korea

    Cilnidipine

    Description References
    Cilnidipine
    Cilnidipine structure
    CAS No.
    132203-70-4
    Chemical Name:
    Cilnidipine
    Synonyms
    CiL;ATELEC;SISCARD;CINALONG;FRC-8653;Sidipine;FRG 8653;nidipine;ilnidipine;CILNDIPINE
    CBNumber:
    CB2193117
    Molecular Formula:
    C27H28N2O7
    Formula Weight:
    492.52
    MOL File:
    132203-70-4.mol

    Cilnidipine Properties

    Melting point:
    97-99°C
    Boiling point:
    652.6±55.0 °C(Predicted)
    Density 
    1.240±0.06 g/cm3(Predicted)
    storage temp. 
    Keep in dark place,Sealed in dry,Room Temperature
    solubility 
    H2O: ≤2mg/mL
    pka
    2.61±0.70(Predicted)
    form 
    powder
    color 
    light yellow
    Merck 
    14,2275
    InChIKey
    KJEBULYHNRNJTE-DHZHZOJOSA-N
    CAS DataBase Reference
    132203-70-4(CAS DataBase Reference)
    FDA UNII
    97T5AZ1JIP
    SAFETY
    • Risk and Safety Statements
    Symbol(GHS) 
    GHS05
    Signal word  Danger
    Hazard statements  H318
    Precautionary statements  P280-P305+P351+P338
    Hazard Codes  Xi
    Risk Statements  41
    Safety Statements  26-39
    WGK Germany  3
    RTECS  US7975550
    HS Code  29333990
    Toxicity LD50 in male, female mice, rats (mg/kg): 5000, 5000, 5000, 4412 orally; 5000 all species s.c.; 1845, 2353, 441, 426 i.p. (Wada)

    Cilnidipine price More Price(7)

    Manufacturer Product number Product description CAS number Packaging Price Updated Buy
    Sigma-Aldrich C1493 Cilnidipine ≥98% (HPLC), powder 132203-70-4 10mg $145 2021-03-22 Buy
    Sigma-Aldrich C1493 Cilnidipine ≥98% (HPLC), powder 132203-70-4 50mg $580 2021-03-22 Buy
    TCI Chemical C2564 Cilnidipine >98.0%(HPLC) 132203-70-4 1g $72 2021-03-22 Buy
    TCI Chemical C2564 Cilnidipine >98.0%(HPLC) 132203-70-4 5g $214 2021-03-22 Buy
    Cayman Chemical 26080 Cilnidipine ≥98% 132203-70-4 1g $99 2021-03-22 Buy

    Cilnidipine Chemical Properties,Uses,Production

    Description

    Clinidipine is a kind of calcium channel blocker. It is a kind of novel calcium antagonist with the blocking effect on both L-type and N-type calcium channels. It is mainly used for the treatment of hypertension. Based on its effect on both N-type and L-type calcium channel, it can dilate both arterioles and venules, further reducing the pressure in the capillary bed. In addition, cilinidipine can attenuate the platelet activation associated with catecholamines.

    References

    https://www.drugbank.ca/drugs/DB09232
    https://en.wikipedia.org/wiki/Cilnidipine

    Description

    Cilnidipine is a dihydropyridine calcium antagonist introduced for the treatment of essential and severe hypertension and hypertension associated with renopathy. Cilnidipine has been demonstrated to exert a potent vasodilating effect by blocking calcium influx via dihydropyridine-sensitive, voltage-dependent calcium channels. Compared to nifedipine and nicardipine, cilnidipine is superior, especially for long-term treatment, due to its characteristics of slow onset and long duration with less cardiodepressant activity. Cilnidipine is reportedly well tolerated with low toxicity. It may also be useful in ischemic heart disease.

    Chemical Properties

    Yellow Crystalline Solid

    Originator

    Fujirebio (Japan)

    Uses

    A dihydropyridine calcium channel blocker

    Uses

    antihypertensive;dihydropyridine calcium channel blocker

    Definition

    ChEBI: A diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive.

    brand name

    Cinalong;Siscard;Atelec

    Biological Activity

    Dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. Lowers mean blood pressure and reduces the size of cerebral infarction in the rat model of focal brain ischemia.

    Cilnidipine Preparation Products And Raw materials

    Raw materials

    Preparation Products


    Cilnidipine Suppliers

    Global( 295)Suppliers
    Supplier Tel Fax Email Country ProdList Advantage
    Henan Tianfu Chemical Co.,Ltd.
    0371-55170693
    0371-55170693 info@tianfuchem.com CHINA 22607 55
    Hangzhou FandaChem Co.,Ltd.
    008615858145714
    +86-571-56059825 fandachem@gmail.com CHINA 8882 55
    Shanxi Naipu Import and Export Co.,Ltd
    +8613734021967
    kaia@neputrading.com CHINA 1011 58
    career henan chemical co
    +86-371-86658258
    sales@coreychem.com CHINA 29961 58
    HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
    +86 19930599843
    cindy@hbyingong.com CHINA 408 58
    Hebei Jimi Trading Co., Ltd.
    +86 319 5273535
    bestoneforyou@sina.com CHINA 292 58
    Hebei Guanlang Biotechnology Co., Ltd.
    +8619930503282
    sales3@crovellbio.com China 5361 58
    Shandong chuangyingchemical Co., Ltd.
    18853181302
    sale@chuangyingchem.com CHINA 5917 58
    Chongqing Chemdad Co., Ltd
    +86-13650506873
    sales@chemdad.com CHINA 37282 58
    Alchem Pharmtech,Inc.
    8485655694
    sales@alchempharmtech.com United States 63726 58

    View Lastest Price from Cilnidipine manufacturers

    Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
    2021-09-29 Cilnidipine
    132203-70-4
    US $0.00 / g 100g 98% 200kg/month WUHAN FORTUNA CHEMICAL CO., LTD
    2021-08-07 Cilnidipine USP/EP/BP
    132203-70-4
    US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
    2021-07-13 Cilnidipine
    132203-70-4
    US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

    132203-70-4(Cilnidipine)Related Search:


    Copyright 2017 ? ChemicalBook. All rights reserved