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    Tetrasodium pyrophosphate

    Tetrasodium pyrophosphate
    Tetrasodium pyrophosphate structure
    CAS No.
    Chemical Name:
    Tetrasodium pyrophosphate
    pyro;TSPP;Nsc56751;victortspp;SODIUM DI;phosphotex;jiaolinsuanan;pyrophosphate;SODIUM DIPHOSPHATE;natriumpyrophosphat
    Molecular Formula:
    Formula Weight:
    MOL File:

    Tetrasodium pyrophosphate Properties

    Melting point:
    80 °C
    Boiling point:
    93.8 °C
    2.53 g/mL at 25 °C(lit.)
    storage temp. 
    Inert atmosphere,Room Temperature
    H2O: 0.1 M at 20 °C, clear, colorless
    Specific Gravity
    PH Range
    Water Solubility 
    Soluble in water. Insoluble in ethyl alcohol.
    Stable. Incompatible with strong oxidizing agents.
    CAS DataBase Reference
    7722-88-5(CAS DataBase Reference)
    FDA 21 CFR
    182.6787; 182.6789; 582.6787; 582.6789; 173.310; 175.210; 175.300; 181.29; 182.70
    SCOGS (Select Committee on GRAS Substances)
    Sodium pyrophosphate, tetrabasic
    Substances Added to Food (formerly EAFUS)
    EWG's Food Scores
    EPA Substance Registry System
    Tetrasodium pyrophosphate (7722-88-5)
    • Risk and Safety Statements
    Signal word  Danger
    Hazard statements  H315-H319-H335-H302-H318
    Precautionary statements  P261-P280a-P304+P340-P405-P501a-P280-P305+P351+P338
    Hazard Codes  Xi,Xn
    Risk Statements  36/37/38-41-22
    Safety Statements  26-36-39
    WGK Germany  3
    RTECS  UX7350000
    TSCA  Yes
    HS Code  28353990

    Tetrasodium pyrophosphate price More Price(12)

    Manufacturer Product number Product description CAS number Packaging Price Updated Buy
    Sigma-Aldrich S6422 Sodium pyrophosphate tetrabasic decahydrate BioXtra, 99.0-103.0% 7722-88-5 100 g $41.2 2021-03-22 Buy
    Sigma-Aldrich P8010 Sodium pyrophosphate tetrabasic ≥95% 7722-88-5 500g $43.8 2021-03-22 Buy
    Sigma-Aldrich 1.06591 tetra-Sodium diphosphate decahydrate for analysis EMSURE? ACS,Reag. Ph Eur 7722-88-5 500 g $90.09 2021-03-22 Buy
    Sigma-Aldrich 71515 Sodium pyrophosphate tetrabasic decahydrate BioUltra, ≥99.5% (T) 7722-88-5 250 g $109 2021-03-22 Buy
    Sigma-Aldrich S6422 Sodium pyrophosphate tetrabasic decahydrate BioXtra, 99.0-103.0% 7722-88-5 500 g $146 2021-03-22 Buy

    Tetrasodium pyrophosphate Chemical Properties,Uses,Production


    Sodium pyrophosphate, also called Tetrasodium pyrophosphate or TSPP is used in the laboratory as a buffering agent. The compound has been shown to be useful in the preparation of an EDTA-sodium pyrophosphate extraction buffer for microcystin analysis of soil samples. Tetrasodium pyrophosphate is an odorless, white powder or granules. It is used in water softener, buffering agent, thickening agent, dispersing agent, wool de-fatting agent, metal cleaner, soap and synthetic detergent builder, general sequestering agent, in electrodeposition of metals. It also acts as a tartar control agent in toothpaste and dental floss. In addition, it is used as a chelating agent in antimicrobial studies. It is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

    Chemical Properties

    Tetrasodium pyrophosphate is a white crystalline powder or colourless crystals with the formula Na4P2O7. It contains the pyrophosphate ion and sodium cation. Toxicity is approximately twice that of table salt when ingested orally. There is also a hydrated form, Na4P2O7.10H2O.
    Tetrasodium pyrophosphate
    Tetrasodium pyrophosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. It is widely used as an emulsifying salt (ES) in process cheese. Common foods containing sodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where it is used as a palatability enhancer. It is the active ingredient in Bakewell, the substitute for baking powder's acid component marketed during shortages in World War II. It is also used in some common baking powders.


    Tetrasodium Pyrophosphate is a coagulant, emulsifier, and sequestrant that is mildly alkaline, with a ph of 10. it is moderately soluble in water, with a solubility of 0.8 g/100 ml at 25°c. it is used as a coagulant in noncooked instant puddings to provide thicken- ing. it functions in cheese to reduce the meltability and fat separa- tion. it is used as a dispersant in malted milk and chocolate drink powders. it prevents crystal formation in tuna. it is also termed sodium pyrophosphate, tetrasodium diphosphate, and tspp.


    Pharmaceutic aid.
    Tetrasodium pyrophosphate (Na4P2O7) is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating. It is also be used as an additive in the food industry.
    Na4P2O7 can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.


    As a water softener; as a metal cleaner; as a dispersing and emulsifying agent.


    Tetrasodium pyrophosphate is formed when pure disodium hydrogen orthophosphate is heated to 500℃ for 5 hours. The product will contain better than 98 per cent Na4P2O7. Crystalline masses large enough for optical measurements are produced by heating in platinum to above the melting point of the tetrasodium pyrophosphate, 800°, and cooling slowly. Higher temperatures or longer heating times do not change the tetrasodium pyrophosphate, as this is the final product in the dehydration of disodium hydrogen orthophosphate.

    General Description

    Odorless, white powder or granules. Mp: 995°C. Density: 2.53 g cm-3. Solubility in water: 3.16 g / 100 mL (cold water); 40.26 g / 100 mL boiling water. Used as a wool de-fatting agent, in bleaching operations, as a food additive. The related substance Tetrasodium pyrophosphate decahydrate (Na4P2O7 0H2O) occurs as colorless transparent crystals. Loses its water when heated to 93.8°C.

    Reactivity Profile

    Tetrasodium pyrophosphate is basic. Reacts exothermically with acids. Incompatible with strong oxidizing agents. Decomposes in ethyl alcohol.


    Toxic by inhalation.

    Health Hazard

    Tetrasodium pyrophosphate (TSPP) is of low toxicity, but the dust may be irritating to the eyes, upper respiratory tract, and skin. Mild to moderate skin and eye irritation have occurred with acute exposure to the dust.

    Safety Profile

    Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. It is not a cholinesterase inhibitor. When heated to decomposition it emits toxic fumes of POx and Na2O.

    Tetrasodium pyrophosphate Preparation Products And Raw materials

    Raw materials

    Preparation Products

    Tetrasodium pyrophosphate Suppliers

    Global( 338)Suppliers
    Supplier Tel Fax Email Country ProdList Advantage
    Hebei Dongdu Import and Export Co. LTD
    15831048222 15831048222
    manager@cndongdu.com CHINA 463 58
    Jiangsu Kolod Food Ingredients Co.,Ltd.
    +8618805133257 +86-518-85110578 18805133257
    +86-518-85110578 sales3257@jskolod.com China 126 60
    Henan Tianfu Chemical Co.,Ltd.
    0371-55170693 info@tianfuchem.com CHINA 22607 55
    Hefei TNJ Chemical Industry Co.,Ltd.
    86-0551-65418684 18949823763
    86-0551-65418684 info@tnjchem.com China 3001 55
    career henan chemical co
    sales@coreychem.com CHINA 29961 58
    Hubei Jusheng Technology Co.,Ltd.
    027-59599243 linda@hubeijusheng.com CHINA 28229 58
    Hebei Guanlang Biotechnology Co., Ltd.
    sales3@crovellbio.com China 5382 58
    hdzhl biotechnology co., ltd
    sales@luchibiology.com CHINA 1275 58
    Chongqing Chemdad Co., Ltd
    sales@chemdad.com CHINA 37282 58
    Shaanxi Dideu Medichem Co. Ltd
    029-88380327 1010@dideu.com CHINA 3993 58

    View Lastest Price from Tetrasodium pyrophosphate manufacturers

    Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
    2021-10-14 Tetrasodium Pyrophosphate
    US $0.80 / KG 1T 96.5% 30 tons Hebei Dongdu Import and Export Co. LTD
    2021-08-26 Tetrasodium pyrophosphate
    US $2.60 / KG 1KG 99.5% 5000kg Hebei Crovell Biotech Co Ltd
    2021-08-12 sodium diphosphateCAS 7722-88-5
    US $900.00 / KG 1KG 99% 20tons Shanghai Dumi Biotechnology Co.,ltd

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