• ChemicalBook
    Chinese Japanese Germany Korea

    Aloe emodin

    Physical and Chemical Properties Rhubarb
    Aloe emodin
    Aloe emodin structure
    CAS No.
    481-72-1
    Chemical Name:
    Aloe emodin
    Synonyms
    RHA;C:C&B63;NSC 38628;Aloe-eModol;ALOE-EMODIN;rhabarberone;ALOE-EMODINE;RHUBARBERONE;ALLYLPYRUVATE;ALOE EMODIN(RG)
    CBNumber:
    CB6727767
    Molecular Formula:
    C15H10O5
    Formula Weight:
    270.24
    MOL File:
    481-72-1.mol

    Aloe emodin Properties

    Melting point:
    223-224°C
    Boiling point:
    373.35°C (rough estimate)
    Density 
    1.3280 (rough estimate)
    refractive index 
    1.5000 (estimate)
    storage temp. 
    2-8°C
    pka
    6.30±0.20(Predicted)
    form 
    neat
    Merck 
    14,306
    BRN 
    2059062
    Stability:
    Hygroscopic
    InChIKey
    YDQWDHRMZQUTBA-UHFFFAOYSA-N
    CAS DataBase Reference
    481-72-1(CAS DataBase Reference)
    FDA UNII
    C8IYT9CR7C
    NCI Dictionary of Cancer Terms
    aloe-emodin
    SAFETY
    • Risk and Safety Statements
    Symbol(GHS) 
    GHS07
    Signal word  Warning
    Hazard statements  H315-H319-H335
    Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P305+P351+P338-P261
    Hazard Codes  Xi
    Risk Statements  36/37/38
    Safety Statements  26-36
    WGK Germany  3
    RTECS  CB6712200
    10
    HS Code  29146990

    Aloe emodin price More Price(52)

    Manufacturer Product number Product description CAS number Packaging Price Updated Buy
    Sigma-Aldrich Y0001596 Diacerein impurity B European Pharmacopoeia (EP) Reference Standard 481-72-1 $190 2021-12-16 Buy
    Sigma-Aldrich 93938 Aloe Emodin analytical standard 481-72-1 10mg $318 2021-12-16 Buy
    Sigma-Aldrich A7687 Aloe Emodin ≥95% (HPLC) 481-72-1 25mg $812 2021-12-16 Buy
    TCI Chemical A2491 Aloe Emodin >97.0%(HPLC) 481-72-1 1g $560 2021-12-16 Buy
    TCI Chemical A2491 Aloe Emodin >97.0%(HPLC) 481-72-1 100mg $140 2021-12-16 Buy

    Aloe emodin Chemical Properties,Uses,Production

    Physical and Chemical Properties

    Aloe emodin aloe is one the major components of the aloe essential oils. It is either presented in aloe in the free form or presented in rhubarb, senna, and aloe in the form of glycosides. The compound precipitated from toluene or ethanol is yellow-orange needles with a relative molecular mass of 270.25 and the melting point of 223~224 ℃. It can be subject to sublimation in the carbon dioxide gas stream. It is easily soluble in hot ethanol, ether, benzene, with the solution exhibiting yellow color. It is also soluble in aqueous ammonia and sulfuric acid with the solution exhibiting crimson color.
    The main active ingredient of aloe is the barbaloin and aloe emodin. The aloe juice has anti-inflammatory effect and can promote healing of skin damage.
    The above information is edited by the Chemicalbook of Dai Xiongfeng.

    Rhubarb

    Rhubarb is a kind of commonly used traditional Chinese medicine. It was initially recorded in the "Shen Nong's Herbal Classic", low-grade product. It is recorded in every generations of Ancient herbal medicine. Rhubarb is the Polygonaceae plant rhubarb Rheum, Rheum tanguticum and the dried roots or rhizomes of medicinal rhubarb Rheum officinale Baill. It is mainly produced in Sichuan, Gansu, Qinghai and other places. Rhubarb has effects such as purge heating and intestine cleaning, blood cooling and detoxification effect, and blood stasis dredging and can be applied to the treatment of the internal heating and constipation, Indigestion, abdominal pain, diarrhea, heat jaundice, vomiting blood, red eyes, swollen throat, abdominal pain, appendicitis, carbuncle swollen boils, blood stasis amenorrhea, and bruises. It can also be applied to external treatment of fire burns, upper gastrointestinal bleeding and so on. We can apply it with raw use or wine-processing, wine steaming or fried carbon.
    Rhubarb has inhibitory effect on most Gram-positive bacteria as well as some Gram-negative bacteria in vitro. Its main active ingredient is anthraquinone derivative with the aloe emodin, emodin and rhein yielding the best efficacy.
    It has inhibition on the murine leukemia P388: people extracted rhein, emodin and aloe emodin from rhubarb. These three kinds of anthraquinone can all reduce the number of cancer cells and the amount of ascites in tumor mice with different extent, in which the effect of rhein is the most significant and the effect of aloe emodin is relatively poor; the effect is generally correlated with the prolonged survival period. Emodin, rhein has a strong inhibitory effect on the biosynthesis of DNA, RNA and protein while aloe emodin strong has a weak inhibitory effect.
    Rheum officinale Baill
    Figure 1 Rheum officinale Baill.

    Chemical Properties

    Orange Solid

    Uses

    Shows significant inhibitory activity against the P-388 leukemia in mice when administered as a suspension in acetone-Tween 80. Has a specific in vitro and in vivo antineuroectodermal tumor activity. Cathartic.

    Definition

    ChEBI: A dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe.

    General Description

    Diacerein is known to be a suitable drug to treat osteoarthritis and prevent vascular diseases. It is a semi-synthetic anthraquinone derivative which acts by inhibiting the production of interleukin-1 and secretion of metalloproteases.

    Biochem/physiol Actions

    Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.

    Aloe emodin Preparation Products And Raw materials

    Raw materials

    Preparation Products


    Aloe emodin Suppliers

    Global( 412)Suppliers
    Supplier Tel Fax Email Country ProdList Advantage
    Shaanxi Yikanglong Biotechnology Co., Ltd.
    17791478691
    yklbiotech@163.com CHINA 297 58
    Zhengzhou Yuanli Biological Technology Co., Ltd
    0086-371-67897895
    info@zzyuanli.cn CHINA 136 58
    Shaanxi Pioneer Biotech Co., Ltd .
    86-13259417953(Whatsapp/Wechat) 86-13259417953(Whatsapp)
    029-84385017 sales@pioneerbiotech.com CHINA 3001 58
    GZ HONCH CHEMICAL TECHNOLOGY CO.,LTD
    +8613437848121
    +8613437848121 chemicalbest@foxmail.com CHINA 226 58
    Henan Tianfu Chemical Co.,Ltd.
    0371-55170693
    0371-55170693 info@tianfuchem.com China 22607 55
    Hangzhou FandaChem Co.,Ltd.
    008615858145714
    +86-571-56059825 fandachem@gmail.com CHINA 9143 55
    Nanjing Finetech Chemical Co., Ltd.
    025-85710122 17714198479
    025-85710122 sales@fine-chemtech.com CHINA 890 55
    Shanghai Zheyan Biotech Co., Ltd.
    18017610038
    zheyansh@163.com CHINA 3623 58
    career henan chemical co
    +86-0371-55982848
    sales@coreychem.com China 29953 58
    Chengdu Biopurify Phytochemicals Ltd.
    18482058008 18080483897
    maggie@biopurify.com China 2712 58

    View Lastest Price from Aloe emodin manufacturers

    Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
    2022-01-04 Aloe-emodin 481-72-1
    481-72-1
    US $20.00 / g 1g ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
    2021-11-30 Aloe emodin
    481-72-1
    US $225.00 / KG 1KG 98% 1-10mt Baoji Guokang Bio-Technology Co., Ltd.
    2021-07-13 Aloe emodin
    481-72-1
    US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

    481-72-1(Aloe emodin)Related Search:


    Copyright 2017 ? ChemicalBook. All rights reserved